Proniosomes: A Novel Vesicular Drug Delivery System

Niosomes – Vesicular Drug Delivery System

At present days drugs are formulated by using different novel drug delivery system (NDDS) which are used for targeting drugs to different organ systems and for controlled /sustained release of drug from the dosage forms. The NDDS can be used to overcome many disadvantages of conventional dosage forms like poor bioavailability, first pass effect, systemic toxicity, degradation of drug in stomach...

Proniosomes as a drug carrier for transdermal delivery of ketorolac.

Niosomes are nonionic surfactant vesicles that have potential applications in the delivery of hydrophobic and hydrophilic drugs. Permeation of a potent nonsteroidal anti-inflammatory, ketorolac, across excised rabbit skin from various proniosome gel formulations was investigated using Franz diffusion cells. Each of the prepared proniosomes significantly improved drug permeation and reduced the ...

Vesicular System-Carrier for Drug Delivery

The application of vesicular system in drug delivery has changed the definitions of diagnosis and treatment in different aspects of biomedical field. The vesicular system as liposomes, niosomes, sphinosomes, transferosomes and pharmacosomes are used to improve the therapeutic index of both existing and new drug molecules by encapsulating an active medicament inside vesicular structure in one su...

Ufasomes: A Vesicular Drug Delivery

Unsaturated fatty acid vesicles (ufasomes) are suspensions of closed lipid bilayers that are composed of fatty acids, and their ionized species (soap) which are restricted to narrow pH range from 7 to 9. In ufasomes, fatty acid molecules are oriented in such a way that their hydrocarbon tails are directed toward the membrane interior and the carboxyl groups are in contact with water. Stable ufa...

Sphingosomes a novel appoach to vesicular drug delivery